hCAI/II-IN-9 is a potent inhibitor of human carbonic anhydrase isoforms I, II, IX, and XII. It exhibits a range of inhibition constants (Ki) from 0.47 to 2.83 nM for hCA XII, indicating strong inhibitory activity, along with notable activity against hCA I, II, and IX. This compound has potential applications in the exploration of various pathologies associated with dysregulated carbonic anhydrase activity, making it valuable for research in cancer, glaucoma, and metabolic disorders.
hCAI/II-IN-9 is a potent inhibitor of human carbonic anhydrase isoforms I, II, IX, and XII. It exhibits a range of inhibition constants (Ki) from 0.47 to 2.83 nM for hCA XII, indicating strong inhibitory activity, along with notable activity against hCA I, II, and IX. This compound has potential applications in the exploration of various pathologies associated with dysregulated carbonic anhydrase activity, making it valuable for research in cancer, glaucoma, and metabolic disorders.
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