HDAC-IN-41

Catalog No.: A26384
HDAC Inhibitor
HDAC-IN-41 is a selective class I histone deacetylase (HDAC) inhibitor, exhibiting IC50 values of 0.62 µM for HDAC1, 1.46 µM for HDAC2, and 0.62 µM for HDAC3. This compound is orally active and demonstrates potential in modulating gene expression through HDAC inhibition. Applications in research include studies on cancer, neurodegenerative diseases, and epigenetic regulation. Notably, HDAC-IN-41 does not exhibit NO releasing activity.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHDAC-IN-41 is a selective class I histone deacetylase (HDAC) inhibitor, exhibiting IC50 values of 0.62 µM for HDAC1, 1.46 µM for HDAC2, and 0.62 µM for HDAC3. This compound is orally active and demonstrates potential in modulating gene expression through HDAC inhibition. Applications in research include studies on cancer, neurodegenerative diseases, and epigenetic regulation. Notably, HDAC-IN-41 does not exhibit NO releasing activity.
Product Information
Catalog NumA26384
FormulaC20H22N4O6S
Molecular Weight446.48
CAS Number2490309-83-4
SMILESO=S(C1=[N+]([O-])ON=C1OCCCCCC(NC2=C(N)C=CC=C2)=O)(C3=CC=CC=C3)=O
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