Idazoxan

Catalog No.: A58313
α2-AR Antagonist
Idazoxan is a potent antagonist of the α2 adrenergic receptor (α2AR) and may also act as an agonist for I2 imidazoline receptors. This compound is relevant for research in the fields of depression and schizophrenia, allowing for investigations into adrenergic modulation and its effects on these mental health disorders. Idazoxan exhibits oral bioactivity, making it suitable for diverse preclinical studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionIdazoxan is a potent antagonist of the α2 adrenergic receptor (α2AR) and may also act as an agonist for I2 imidazoline receptors. This compound is relevant for research in the fields of depression and schizophrenia, allowing for investigations into adrenergic modulation and its effects on these mental health disorders. Idazoxan exhibits oral bioactivity, making it suitable for diverse preclinical studies.
Product Information
Catalog NumA58313
FormulaC11H12N2O2
Molecular Weight204.23
CAS Number79944-58-4
SMILESC1(OCC(C2=NCCN2)O3)=C3C=CC=C1
SynonymsRX 781094
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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