Imazalil is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits significant oral bioactivity and strongly activates the mouse pregnane X receptor (mPXR), while having minimal effect on the mouse constitutive androstane receptor (mCAR). Research indicates that Imazalil can induce developmental abnormalities, disrupt gut microbiota, and interfere with hepatic metabolism, making it valuable for studies on environmental toxicology and agricultural practices.
Imazalil is a potent fungicide that primarily targets fungal pathogens in agricultural settings. It exhibits significant oral bioactivity and strongly activates the mouse pregnane X receptor (mPXR), while having minimal effect on the mouse constitutive androstane receptor (mCAR). Research indicates that Imazalil can induce developmental abnormalities, disrupt gut microbiota, and interfere with hepatic metabolism, making it valuable for studies on environmental toxicology and agricultural practices.
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