Imipramine-d6 is the deuterium-labeled form of Imipramine hydrochloride, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. It exhibits notable antitumor activity as a Fascin1 inhibitor, promoting autophagy in U-87MG glioma cells and inducing apoptosis in HL-60 cells. Additionally, Imipramine-d6 demonstrates neuroprotective and immunomodulatory effects, making it valuable for research into depression, cancer, and neurodegenerative disorders.
Imipramine-d6 is the deuterium-labeled form of Imipramine hydrochloride, a tricyclic antidepressant that primarily acts as a serotonin transporter inhibitor with an IC50 value of 32 nM. It exhibits notable antitumor activity as a Fascin1 inhibitor, promoting autophagy in U-87MG glioma cells and inducing apoptosis in HL-60 cells. Additionally, Imipramine-d6 demonstrates neuroprotective and immunomodulatory effects, making it valuable for research into depression, cancer, and neurodegenerative disorders.
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