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Biological Activity
INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.19 mL | 110.95 mL | 221.9 mL |
| 0.5 mM | 4.44 mL | 22.19 mL | 44.38 mL |
| 1 mM | 2.22 mL | 11.1 mL | 22.19 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.44 mL |
*The above data is based on the productmolecular weight 450.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21168 |
|---|---|
| Actions | Agonist |
| CAS No. | 1199796-29-6 |
| Formula | C27H46O5 |
| M. Wt | 450.65 |
| Purity | >98% |
| Synonyms | S-EMCA, INT777, INT 777 |
| SMILES | O[C@@H]1CC[C@@]2(C)[C@@]([C@@H](CC)[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@@H]4[C@H](C)C[C@H](C)C(O)=O)([H])C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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