Junceellolide C is a transcription inhibitor targeting cccDNA, effectively impeding HBV DNA replication. It demonstrates significant reductions in supernatant HBV RNA, with EC50 values of 5.19 μM and 3.52 μM in HepAD38 cells. This compound is recognized for its potent anti-HBV activity, making it a valuable tool for research into therapeutic strategies against hepatitis B virus infections.
Junceellolide C is a transcription inhibitor targeting cccDNA, effectively impeding HBV DNA replication. It demonstrates significant reductions in supernatant HBV RNA, with EC50 values of 5.19 μM and 3.52 μM in HepAD38 cells. This compound is recognized for its potent anti-HBV activity, making it a valuable tool for research into therapeutic strategies against hepatitis B virus infections.
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