KIRA-7

Name: KIRA-7
Brand: Adooq Bioscience
SKU: A54710
Rating: 5 (288 reviews)

Catalog No.: A54710

IRE1α Inhibitor

KIRA-7 is an imidazopyrazine compound that functions as an allosteric inhibitor of IRE1α kinase, exhibiting an IC50 of 110 nM. By inhibiting the RNase activity of IRE1α, KIRA-7 demonstrates significant anti-fibrotic effects. This reagent is valuable for research focusing on cellular stress responses and the unfolded protein response.

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Grouped product items
Size	Price	Stock
5mg	$335.00	In stock
10mg	$565.00	In stock
25mg	$1,125.00	In stock
50mg	$1,460.00	In stock
100mg	$2,240.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	KIRA-7 is an imidazopyrazine compound that functions as an allosteric inhibitor of IRE1α kinase, exhibiting an IC50 of 110 nM. By inhibiting the RNase activity of IRE1α, KIRA-7 demonstrates significant anti-fibrotic effects. This reagent is valuable for research focusing on cellular stress responses and the unfolded protein response.

Product Information

Catalog Num	A54710
Formula	C27H23FN6O
Molecular Weight	466.51
CAS Number	1937235-76-1
SMILES	O=C(NC1=CC=CC(F)=C1)NC2=C3C=CC=CC3=C(C4=C5C(N)=NC=CN5C(C6(C)CC6)=N4)C=C2

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