KRAS G12C Inhibitor 47 is a selective inhibitor targeting the KRAS G12C mutation, exhibiting an IC50 of 0.172 µM. It effectively inhibits p-ERK signaling, with IC50 values of 0.046 µM in MIA PaCA-2 cells and 69.8 µM in A549 cells. This compound is a valuable tool for researching therapeutic strategies in pancreatic, colorectal, and lung cancers.
KRAS G12C Inhibitor 47 is a selective inhibitor targeting the KRAS G12C mutation, exhibiting an IC50 of 0.172 µM. It effectively inhibits p-ERK signaling, with IC50 values of 0.046 µM in MIA PaCA-2 cells and 69.8 µM in A549 cells. This compound is a valuable tool for researching therapeutic strategies in pancreatic, colorectal, and lung cancers.
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