L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is a stable isotope-labeled variant of L-Azidohomoalanine, featuring both 13C and 15N isotopes. This reagent acts as a versatile PROTAC linker, facilitating the synthesis of protein-targeting chimeras. It serves as a click chemistry tool, incorporating an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-containing molecules, expanding its utility in biological research applications.
L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is a stable isotope-labeled variant of L-Azidohomoalanine, featuring both 13C and 15N isotopes. This reagent acts as a versatile PROTAC linker, facilitating the synthesis of protein-targeting chimeras. It serves as a click chemistry tool, incorporating an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-containing molecules, expanding its utility in biological research applications.
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