Lactosyl-C18-sphingosine is a bioactive sphingolipid that functions as a lysoganglioside, specifically a form of lactosylceramide without the fatty acyl group. It exhibits the ability to reduce the viability of human neutrophils in a concentration-dependent manner at low micromolar concentrations (1-50 μM). Unlike its counterpart, lactosylceramide, Lactosyl-C18-sphingosine does not affect protein synthesis or cell proliferation in cardiomyocytes, making it a unique tool for studying sphingolipid signaling and metabolism in various biological contexts.
Lactosyl-C18-sphingosine is a bioactive sphingolipid that functions as a lysoganglioside, specifically a form of lactosylceramide without the fatty acyl group. It exhibits the ability to reduce the viability of human neutrophils in a concentration-dependent manner at low micromolar concentrations (1-50 μM). Unlike its counterpart, lactosylceramide, Lactosyl-C18-sphingosine does not affect protein synthesis or cell proliferation in cardiomyocytes, making it a unique tool for studying sphingolipid signaling and metabolism in various biological contexts.
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