Lexibulin dihydrochloride

Catalog No.: A21774

tubulin polymerisation inhibitor

Lexibulin dihydrochloride

Lexibulin dihydrochloride Chemical Structure

CAS NO. 917111-49-0

Lexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Lexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.71 mL 98.53 mL 197.06 mL
0.5 mM 3.94 mL 19.71 mL 39.41 mL
1 mM 1.97 mL 9.85 mL 19.71 mL
5 mM 0.39 mL 1.97 mL 3.94 mL

*The above data is based on the productmolecular weight 507.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21774
Actions Inhibitor
M. Wt 507.46
Formula C24H32Cl2N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 917111-49-0
Synonyms CYT-997 dihydrochloride, CYT997, CYT 997
SMILES CCC[[email protected]](NC1=C(C)C=NC(C2=CC=C(NC(NCC)=O)C(OC)=C2)=N1)C3=CN=CC=C3.[H]Cl.[H]Cl

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