LIMK-IN-1

Catalog No.: A36815
LIMK Inhibitor
LIMK-IN-1 is a potent inhibitor of LIM-Kinase (LIMK), exhibiting IC50 values of 0.5 nM for LIMK1 and 0.9 nM for LIMK2. This compound is primarily utilized in research related to ocular hypertension and associated glaucoma, contributing to studies aimed at understanding the role of LIMK in these conditions. Its high specificity and efficacy make it a valuable tool for investigating the molecular pathways involved in ocular diseases.
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$90.00
In stock
50mg
$125.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLIMK-IN-1 is a potent inhibitor of LIM-Kinase (LIMK), exhibiting IC50 values of 0.5 nM for LIMK1 and 0.9 nM for LIMK2. This compound is primarily utilized in research related to ocular hypertension and associated glaucoma, contributing to studies aimed at understanding the role of LIMK in these conditions. Its high specificity and efficacy make it a valuable tool for investigating the molecular pathways involved in ocular diseases.
Product Information
Catalog NumA36815
FormulaC20H21BrN8
Molecular Weight453.34
CAS Number1116571-01-7
SMILESCC1=CNC2=NC=NC(N3C[C@H](C)N(/C(NC4=CC=CC(Br)=C4)=N\C#N)CC3)=C21
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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