LIMK1 inhibitor BMS-4 is a selective inhibitor of LIM Kinases (LIMK1 and LIMK2). By inhibiting LIMK1, BMS-4 effectively blocks the phosphorylation of cofilin, a critical substrate, thereby modulating actin dynamics. It has demonstrated noncytotoxicity in A549 cells, making it a valuable tool for investigating LIMK-related pathways and their roles in cancer cell migration and invasion.
LIMK1 inhibitor BMS-4 is a selective inhibitor of LIM Kinases (LIMK1 and LIMK2). By inhibiting LIMK1, BMS-4 effectively blocks the phosphorylation of cofilin, a critical substrate, thereby modulating actin dynamics. It has demonstrated noncytotoxicity in A549 cells, making it a valuable tool for investigating LIMK-related pathways and their roles in cancer cell migration and invasion.
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