- Cat. No.
- A60851
Resolvin D5 n-3 DPA
Resolvin D5 n-3 DPA is a specialized proresolving lipid mediator derived from docosapentaenoic acid. It acts as an agonist for GPR101, GPR12, and GPR84, displaying EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent anti-inflammatory and pro-resolution properties, effectively reducing cell adhesion on TNF-α-activated human endothelial monolayers. Furthermore, Resolvin D5 n-3 DPA enhances leukocyte functions, promoting the phagocytic activity of neutrophils and macrophages, making it valuable in research related to intestinal inflammation.
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