MC1568

Catalog No.: A10560

HDAC Inhibitor

MC1568

MC1568 Chemical Structure

CAS NO. 852475-26-4

MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.

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10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $150.00

Special Price $120.00

100 mg

Regular Price: $280.00

Special Price $224.00

10mM * 1mL in DMSO

Regular Price: $50.00

Special Price $40.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Minoru Ueda, .et al. The Distinct Roles of Class I and II RPD3-Like Histone Deacetylases in Salinity Stress Response, Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096
  • S Ishikawa, .et al. Statins inhibit tumor progression via an enhancer of zeste homolog 2-mediated epigenetic alteration in colorectal cancer, Int J Cancer., 2014, 135(11): 2528-2536 PMID: 24346863
  • Usui T, .et al. Histone deacetylase 4 controls neointimal hyperplasia via stimulating proliferation and migration of vascular smooth muscle cells., Hypertension., 2014, Feb;63(2):397-403 PMID: 24166750

Biological Activity

MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.
Targets
HD1-A (Maize) (Cell-free assay) HD1-B (Maize) (Cell-free assay)
100 nM3.4 μM
In vitro (25°C) DMSO 12 mg/mL (38.18 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.82 mL 159.08 mL 318.17 mL
0.5 mM 6.36 mL 31.82 mL 63.63 mL
1 mM 3.18 mL 15.91 mL 31.82 mL
5 mM 0.64 mL 3.18 mL 6.36 mL

*The above data is based on the productmolecular weight 314.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10560
Actions Inhibitor
CAS No. 852475-26-4
Formula C17H15FN2O3
M. Wt 314.3
Purity >98%
Synonyms MC-1568
SMILES CN1C=C(C=C1/C=C/C(=O)NO)/C=C/C(=O)C2=CC(=CC=C2)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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