N-Desethyl Sunitinib-d5 hydrochloride is a deuterated analog of N-Desethyl Sunitinib, a significant metabolite of the multi-targeted kinase inhibitor, sunitinib. This compound functions primarily as a stable isotope for quantitative analysis in pharmacokinetic studies. It demonstrates potent inhibition of vascular endothelial growth factor receptors (VEGFR) as well as platelet-derived growth factor receptor beta (PDGFRβ) and KIT, making it useful in research involving angiogenesis and tumor progression.
N-Desethyl Sunitinib-d5 hydrochloride is a deuterated analog of N-Desethyl Sunitinib, a significant metabolite of the multi-targeted kinase inhibitor, sunitinib. This compound functions primarily as a stable isotope for quantitative analysis in pharmacokinetic studies. It demonstrates potent inhibition of vascular endothelial growth factor receptors (VEGFR) as well as platelet-derived growth factor receptor beta (PDGFRβ) and KIT, making it useful in research involving angiogenesis and tumor progression.
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