NC-002 is a cell-permeable trypsin-like proteasome inhibitor that selectively targets the proteasome while sparing lysosomal cysteine proteases. This epoxyketone derivative of Leupeptin enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib, making it a valuable tool for cancer research. NC-002's unique mechanism offers potential insights into proteasome-related pathways and therapeutic strategies in oncology.
NC-002 is a cell-permeable trypsin-like proteasome inhibitor that selectively targets the proteasome while sparing lysosomal cysteine proteases. This epoxyketone derivative of Leupeptin enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib, making it a valuable tool for cancer research. NC-002's unique mechanism offers potential insights into proteasome-related pathways and therapeutic strategies in oncology.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
