Bortezomib (Velcade)

Catalog No.: A10160
Proteasome inhibitor
Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome
Grouped product items
Product Name Price Stock Qty
Bortezomib 5mg
$30.00
In stock
Bortezomib 10mg
$58.00
In stock
Bortezomib 25mg
$98.00
In stock
Bortezomib 100mg
$160.00
In stock
Bortezomib (Velcade) 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's Bortezomib (Velcade) has been cited by 15 publications
  • Tomoyuki Abe, .et al. , Eur J Pharmacol, 2022, Nov 15;935:175321 PMID: 36228744
  • Yoshitaka Sato, .et al. , Cell Commun Signal, 2022, Jun 21;20(1):95 PMID: 35729616
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Shin-Ichi Makino, .et al. , J Am Soc Nephrol, 2021, Mar;32(3):597-613 PMID: 33510039
  • Yusuke Yamashita, .et al. , Int J Mol Sci, 2020, Sep; 21(17): 6314 PMID: 32878237
  • Nandini Verma, .et al. , Sci Adv, 2020, 6 : eaba8968
  • A Hayano, .et al. , Int J Clin Oncol, 2019, 1-10 PMID: 30993483
  • Hiroshi Fukamachi, .et al. , J Exp Clin Cancer Res, 2019, 38:127 PMID: 30866995
  • Y Sato, .et al. , J Virol, 2019, Jan 30. pii: JVI.01707-18 PMID: 30700607
  • Takashi Azuma, .et al. , SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Wenhan Deng, .et al. , Transl Oncol, 2018, Oct; 11(5): 1147-1154 PMID: 30055346
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
  • Hokyung K. Chung, .et al. , Nat Chem Biol, 2015, Sep; 11(9): 713-720 PMID: 26214256
  • S Raz, .et al. , Cell Death Dis., 2014, 5(2): e1067 PMID: 24556682
  • Biological Activity
    Discription Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome
    Targets
    Target Value
    Product Information
    Catalog Num A10160
    Formula C19H25BN4O4
    Molecular Weight 384.2
    CAS Number 179324-69-7
    SMILES B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
    Synonyms MG-341, PS-341
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 66 mg/mL (171.77 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.03 mL 130.14 mL 260.28 mL
    0.5 mM 5.21 mL 26.03 mL 52.06 mL
    1 mM 2.6 mL 13.01 mL 26.03 mL
    5 mM 0.52 mL 2.6 mL 5.21 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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