PR-171 (Carfilzomib)

Catalog No.: A11278
Proteasome inhibitor
PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.
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PR-171 5mg
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PR-171 10mg
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PR-171 25mg
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PR-171 50mg
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PR-171 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's PR-171 (Carfilzomib) has been cited by 6 publications
  • Andrew Thorne, .et al. , PLoS One, 2023, Jun 8;18(6):e0286783 PMID: 37289679
  • Mahmood Barani, .et al. , J Drug Deliv Sci Technol, 2023, 81: 104268
  • Ori Kalid, .et al. , Chem Biol Drug Des, 2022, Mar 24 PMID: 35322538
  • Abbas Rahdar, .et al. , Journal of Molecular Liquids, 2022, 346: 118271
  • Sadegh Zarei, .et al. , J Appl Biotechnol Rep, 2019, June;6(2):45-49
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
  • Biological Activity
    Discription PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.
    Target Value
    Product Information
    Catalog Num A11278
    Formula C40H57N5O7
    Molecular Weight 719.9
    CAS Number 868540-17-4
    SMILES CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
    Synonyms PR-171-007

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 46 mg/mL (63.89 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+2%Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 13.89 mL 69.45 mL 138.91 mL
    0.5 mM 2.78 mL 13.89 mL 27.78 mL
    1 mM 1.39 mL 6.95 mL 13.89 mL
    5 mM 0.28 mL 1.39 mL 2.78 mL
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