Signaling Pathway
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| Discription | NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. | ||
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| Catalog Num | A20600 |
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| Formula | C19H23N3O2 |
| Molecular Weight | 325.4 |
| CAS Number | 537034-15-4 |
| SMILES | O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=CC=C2)=O |
| Synonyms | NKL22, NKL-22 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 62 mg/mL (190.53 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (9.21 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.73 mL | 153.66 mL | 307.31 mL |
| 0.5 mM | 6.15 mL | 30.73 mL | 61.46 mL |
| 1 mM | 3.07 mL | 15.37 mL | 30.73 mL |
| 5 mM | 0.61 mL | 3.07 mL | 6.15 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
