Nur77 Modulator 1 is an effective modulator of Nur77, characterized by a binding affinity of KD = 3.58 μM. This compound up-regulates Nur77 expression and influences its sub-cellular localization, leading to Nur77-dependent endoplasmic reticulum (ER) stress and autophagy, ultimately promoting apoptotic processes in cells. Its notable anti-hepatoma activity makes it a valuable tool for research in cancer biology and cellular stress responses.
Nur77 Modulator 1 is an effective modulator of Nur77, characterized by a binding affinity of KD = 3.58 μM. This compound up-regulates Nur77 expression and influences its sub-cellular localization, leading to Nur77-dependent endoplasmic reticulum (ER) stress and autophagy, ultimately promoting apoptotic processes in cells. Its notable anti-hepatoma activity makes it a valuable tool for research in cancer biology and cellular stress responses.
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