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Chelators & Bifunctional Chelators

Chelators and bifunctional chelators bind metal ions through several donor atoms of one molecule. The coordinating groups hold the ion in a ring structure, which lowers its free concentration and changes its redox behavior and availability. Calcium-selective chelators such as BAPTA buffer intracellular calcium in cell biology and electrophysiology experiments. Iron chelators form the largest group here and include HBED, deferitazole, VK-28 and CN128 hydrochloride, used in studies of iron metabolism and oxidative stress. Penicillamine and succimer bind copper, lead and other heavy metals through thiol and amine donors. Bifunctional chelators add a reactive group for coupling to peptides or proteins, as in DTPA-tetra (t-Bu ester), a protected form of diethylenetriaminepentaacetic acid (DTPA).

Cat. No.

A46590

CAS No.

134-31-6

8-Hydroxyquinoline hemisulfate

Synonyms: 8-Quinolinol hemisulfate

8-Hydroxyquinoline hemisulfate is a monoprotic bidentate chelating agent that exhibits notable antiseptic, disinfectant, and pesticidal properties. It functions as a transcription inhibitor, making it useful in studies involving gene expression regulation and molecular biology applications. This compound is commonly employed in research focused on metal ion chelation and various biochemical assays.

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100 mg

$20.00

500 mg

$25.00

All 5 sizes
Cat. No.

A88977

CAS No.

58105-91-2

Hexacyclen hexahydrochloride

Synonyms: Hexaaza-18-crown-6 hexahydrochloride; 1,4,7,10,13,16-Hexaazacyclooctadecane hexahydrochloride

Hexacyclen hexahydrochloride is a chelating agent that features a macrocyclic structure composed of six nitrogen-containing rings. This compound effectively binds metal ions, making it valuable for research applications involving the study of protein and enzyme structure and function. Additionally, Hexacyclen hexahydrochloride has been identified as an inhibitor of cancer, further expanding its utility in biochemical research and therapeutic exploration.

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50 mg

$260.00

100 mg

$350.00

All 2 sizes

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