Drug Intermediate

Drug intermediates are building blocks and reagents used to synthesize active compounds and their analogs. The category covers small aromatic ketones and acids, aliphatic keto acids, sugars and amino acid-related compounds. 2'-Hydroxyacetophenone, an ortho-substituted aromatic ketone, is a common precursor of chromones and flavonoids. Phenylglyoxylic acid carries an α-keto acid group on a benzene ring, while levulinic acid is a biomass-derived keto acid used as a platform chemical. Carbohydrate intermediates include DL-Xylose and N-acetyl-D-mannosamine, a biosynthetic precursor of sialic acids. Several entries are also endogenous metabolites or salts, so they serve biochemical as well as synthetic work. Compounds built by modifying an existing drug structure are listed under Drug Derivative.

3 Items

  • STING agonist-33
    Cat. No.
    A65602

    STING agonist-33

    STING agonist-33 is a potent agonist of STING (stimulator of interferon genes) derived from 4-ethyl-2-methylthiazole-5-carboxylic acid. It acts by activating the STING pathway, which plays a crucial role in the innate immune response by promoting the production of type I interferons. This reagent is valuable for research applications focused on immune modulation, cancer therapy, and infectious diseases, as it can enhance the body's antiviral and antitumor defenses.

    Out of stock

    All 3 sizes
  • Benzyl piperazine-1-carboxylate
    Cat. No.
    A86776

    Benzyl piperazine-1-carboxylate

    Benzyl piperazine-1-carboxylate is a synthetic intermediate primarily utilized in the development of melanocortin-4 (MC4) receptor antagonists. Its structural properties make it valuable in biochemical research aimed at understanding and modulating MC4 receptor activity, which is implicated in various physiological processes including appetite regulation and energy homeostasis. This compound serves as a critical building block for the synthesis of novel therapeutic candidates targeting the MC4 receptor.

    1 mg
    $20.00
    25 g
    $25.00
    All 5 sizes
  • 2-Chloro-1,4-naphthoquinone
    Cat. No.
    A86933

    2-Chloro-1,4-naphthoquinone

    2-Chloro-1,4-naphthoquinone is a reactive intermediate with potent cytotoxic properties, functioning as a vitamin K-dependent carboxylation antagonist. It exhibits an IC50 value of 146 μM, demonstrating its effectiveness in inhibiting enzymatic processes reliant on vitamin K. This compound is valuable for biochemical research focused on understanding carboxylation mechanisms and exploring potential therapeutic applications in cancer biology.

    100 mg
    $20.00
    500 mg
    $30.00
    All 4 sizes

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