Drug Intermediate

Cat. No.

A86776

CAS No.

31166-44-6

Benzyl piperazine-1-carboxylate

Benzyl piperazine-1-carboxylate is a synthetic intermediate primarily utilized in the development of melanocortin-4 (MC4) receptor antagonists. Its structural properties make it valuable in biochemical research aimed at understanding and modulating MC4 receptor activity, which is implicated in various physiological processes including appetite regulation and energy homeostasis. This compound serves as a critical building block for the synthesis of novel therapeutic candidates targeting the MC4 receptor.

Cat. No.

A86933

CAS No.

1010-60-2

2-Chloro-1,4-naphthoquinone

2-Chloro-1,4-naphthoquinone is a reactive intermediate with potent cytotoxic properties, functioning as a vitamin K-dependent carboxylation antagonist. It exhibits an IC50 value of 146 μM, demonstrating its effectiveness in inhibiting enzymatic processes reliant on vitamin K. This compound is valuable for biochemical research focused on understanding carboxylation mechanisms and exploring potential therapeutic applications in cancer biology.

Cat. No.

A97856

CAS No.

637-88-7

1,4-Cyclohexanedione

1,4-Cyclohexanedione serves as a crucial drug intermediate due to its role as a substrate for the EryKR1 domain. This compound exhibits unique biocatalytic activity and stereospecificity, making it valuable for various synthetic applications in pharmaceutical research. Its ability to participate in stereochemical transformations further supports its utility in the development of complex organic molecules.

Cat. No.

A98382

CAS No.

498-62-4

3-Thiophenecarboxaldehyde

Synonyms: 3-TC

3-Thiophenecarboxaldehyde is a thiophene derivative that serves as a substrate for biocatalytic reduction to 3-thiophenemethanol, facilitated by Pseudomonas putida S12 cells. This compound functions as an important intermediate in synthetic pathways. However, it exhibits toxicity toward Pseudomonas putida S12 at elevated concentrations, negatively impacting specific growth rates and final biomass yields. Its unique properties make it useful for research in biocatalysis and metabolic engineering.

Cat. No.

A99692

CAS No.

5588-21-6

Cintriamide

Synonyms: Cintramide

Cintriamide is a crucial synthesis intermediate used in the preparation of photoswitchable epothilone-based microtubule stabilizers. Its unique chemical properties facilitate the development of novel compounds targeting microtubule dynamics, making it vital for advancing research in cancer therapeutics and related fields. This compound serves as a valuable building block for scientists exploring new therapeutic avenues in antineoplastic drug development.

Cat. No.

B10424

CAS No.

863238-52-2

Sal-AMP

Sal-AMP is an acyl-adenylate intermediate that serves as a substrate for MbtA, facilitating the loading onto the thiolation domain of MbtB. This compound plays a critical role in the biosynthetic pathway of mycobacterial compounds and is valuable for research investigating tuberculosis and related bacterial processes. Its use can aid in understanding the mechanisms of mycobacterial metabolism and potential drug targets.