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Drug Intermediate

Drug intermediates are building blocks and reagents used to synthesize active compounds and their analogs. The category covers small aromatic ketones and acids, aliphatic keto acids, sugars and amino acid-related compounds. 2'-Hydroxyacetophenone, an ortho-substituted aromatic ketone, is a common precursor of chromones and flavonoids. Phenylglyoxylic acid carries an α-keto acid group on a benzene ring, while levulinic acid is a biomass-derived keto acid used as a platform chemical. Carbohydrate intermediates include DL-Xylose and N-acetyl-D-mannosamine, a biosynthetic precursor of sialic acids. Several entries are also endogenous metabolites or salts, so they serve biochemical as well as synthetic work. Compounds built by modifying an existing drug structure are listed under Drug Derivative.

3 Items

  • Benzyl piperazine-1-carboxylate
    Cat. No.
    A86776
    CAS No.
    31166-44-6

    Benzyl piperazine-1-carboxylate

    Benzyl piperazine-1-carboxylate is a synthetic intermediate primarily utilized in the development of melanocortin-4 (MC4) receptor antagonists. Its structural properties make it valuable in biochemical research aimed at understanding and modulating MC4 receptor activity, which is implicated in various physiological processes including appetite regulation and energy homeostasis. This compound serves as a critical building block for the synthesis of novel therapeutic candidates targeting the MC4 receptor.

    In stock View Details
    1 mg
    $20.00
    25 g
    $25.00
    All 5 sizes
  • 2-Chloro-1,4-naphthoquinone
    Cat. No.
    A86933
    CAS No.
    1010-60-2

    2-Chloro-1,4-naphthoquinone

    2-Chloro-1,4-naphthoquinone is a reactive intermediate with potent cytotoxic properties, functioning as a vitamin K-dependent carboxylation antagonist. It exhibits an IC50 value of 146 μM, demonstrating its effectiveness in inhibiting enzymatic processes reliant on vitamin K. This compound is valuable for biochemical research focused on understanding carboxylation mechanisms and exploring potential therapeutic applications in cancer biology.

    In stock View Details
    100 mg
    $20.00
    500 mg
    $30.00
    All 4 sizes
  • Cintriamide
    Cat. No.
    A99692
    CAS No.
    5588-21-6

    Cintriamide

    Synonyms: Cintramide

    Cintriamide is a crucial synthesis intermediate used in the preparation of photoswitchable epothilone-based microtubule stabilizers. Its unique chemical properties facilitate the development of novel compounds targeting microtubule dynamics, making it vital for advancing research in cancer therapeutics and related fields. This compound serves as a valuable building block for scientists exploring new therapeutic avenues in antineoplastic drug development.

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    Out of stock

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