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Drug Intermediate

Drug intermediates are building blocks and reagents used to synthesize active compounds and their analogs. The category covers small aromatic ketones and acids, aliphatic keto acids, sugars and amino acid-related compounds. 2'-Hydroxyacetophenone, an ortho-substituted aromatic ketone, is a common precursor of chromones and flavonoids. Phenylglyoxylic acid carries an α-keto acid group on a benzene ring, while levulinic acid is a biomass-derived keto acid used as a platform chemical. Carbohydrate intermediates include DL-Xylose and N-acetyl-D-mannosamine, a biosynthetic precursor of sialic acids. Several entries are also endogenous metabolites or salts, so they serve biochemical as well as synthetic work. Compounds built by modifying an existing drug structure are listed under Drug Derivative.

4 Items

  • STING agonist-33
    Cat. No.
    A65602
    CAS No.
    2591300-32-0

    STING agonist-33

    STING agonist-33 is a potent agonist of STING (stimulator of interferon genes) derived from 4-ethyl-2-methylthiazole-5-carboxylic acid. It acts by activating the STING pathway, which plays a crucial role in the innate immune response by promoting the production of type I interferons. This reagent is valuable for research applications focused on immune modulation, cancer therapy, and infectious diseases, as it can enhance the body's antiviral and antitumor defenses.

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  • 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
    Cat. No.
    A98838
    CAS No.
    174264-46-1

    4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene

    4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is a silyl ether derivative of Raloxifene formed through its reaction with tert-butyldimethylsilyl chloride. This compound plays a crucial role in the synthesis of Raloxifene 6-glucuronide, facilitating studies on Raloxifene metabolism and pharmacokinetics. Its utility in chemical research underscores its significance in the exploration of selective estrogen receptor modulators and their applications in therapeutic contexts.

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    25 mg
    $115.00
    50 mg
    $155.00
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  • Cintriamide
    Cat. No.
    A99692
    CAS No.
    5588-21-6

    Cintriamide

    Synonyms: Cintramide

    Cintriamide is a crucial synthesis intermediate used in the preparation of photoswitchable epothilone-based microtubule stabilizers. Its unique chemical properties facilitate the development of novel compounds targeting microtubule dynamics, making it vital for advancing research in cancer therapeutics and related fields. This compound serves as a valuable building block for scientists exploring new therapeutic avenues in antineoplastic drug development.

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  • Phthalide
    Cat. No.
    B21764
    CAS No.
    87-41-2

    Phthalide

    Phthalide is a versatile chemical scaffold known for its potential in synthesizing various derivatives with significant biological activities. Its derivatives have been explored for applications as anti-inflammatory agents, antimicrobial compounds, antioxidants, and modulators of the blood-tumor barrier. Phthalide serves as a foundational structure in medicinal chemistry, facilitating the development of novel therapeutic agents.

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    10 g
    $20.00
    25 g
    $30.00
    All 4 sizes

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