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Drug Intermediate

Drug intermediates are building blocks and reagents used to synthesize active compounds and their analogs. The category covers small aromatic ketones and acids, aliphatic keto acids, sugars and amino acid-related compounds. 2'-Hydroxyacetophenone, an ortho-substituted aromatic ketone, is a common precursor of chromones and flavonoids. Phenylglyoxylic acid carries an α-keto acid group on a benzene ring, while levulinic acid is a biomass-derived keto acid used as a platform chemical. Carbohydrate intermediates include DL-Xylose and N-acetyl-D-mannosamine, a biosynthetic precursor of sialic acids. Several entries are also endogenous metabolites or salts, so they serve biochemical as well as synthetic work. Compounds built by modifying an existing drug structure are listed under Drug Derivative.

3 Items

  • 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
    Cat. No.
    A98838
    CAS No.
    174264-46-1

    4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene

    4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is a silyl ether derivative of Raloxifene formed through its reaction with tert-butyldimethylsilyl chloride. This compound plays a crucial role in the synthesis of Raloxifene 6-glucuronide, facilitating studies on Raloxifene metabolism and pharmacokinetics. Its utility in chemical research underscores its significance in the exploration of selective estrogen receptor modulators and their applications in therapeutic contexts.

    In stock View Details
    25 mg
    $115.00
    50 mg
    $155.00
    All 4 sizes
  • 3-(4-(5-Hydroxypent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
    Cat. No.
    B10250
    CAS No.
    2138441-30-0

    3-(4-(5-Hydroxypent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

    3-(4-(5-Hydroxypent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione acts as a crucial intermediate in the synthesis of RET degraders. This compound is integral for researchers developing targeted therapies involving RET protein degradation. Its utility in synthetic pathways underscores its significance in chemical biology and therapeutic research applications.

    In stock View Details
    5 mg
    $50.00
    10 mg
    $80.00
    All 4 sizes
  • Phthalide
    Cat. No.
    B21764
    CAS No.
    87-41-2

    Phthalide

    Phthalide is a versatile chemical scaffold known for its potential in synthesizing various derivatives with significant biological activities. Its derivatives have been explored for applications as anti-inflammatory agents, antimicrobial compounds, antioxidants, and modulators of the blood-tumor barrier. Phthalide serves as a foundational structure in medicinal chemistry, facilitating the development of novel therapeutic agents.

    In stock View Details
    10 g
    $20.00
    25 g
    $30.00
    All 4 sizes

3 Items

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