Patulin is a mycotoxin synthesized by various fungal species, including Aspergillus, Penicillium, and Byssochlamys. It is known to induce chromosome breakage and mutations, exhibiting teratogenic and cytotoxic effects. Patulin triggers autophagy-dependent apoptosis via the lysosomal-mitochondrial axis, leading to DNA damage. This compound is relevant for research into the mechanisms of mycotoxin toxicity and apoptosis.
Patulin is a mycotoxin synthesized by various fungal species, including Aspergillus, Penicillium, and Byssochlamys. It is known to induce chromosome breakage and mutations, exhibiting teratogenic and cytotoxic effects. Patulin triggers autophagy-dependent apoptosis via the lysosomal-mitochondrial axis, leading to DNA damage. This compound is relevant for research into the mechanisms of mycotoxin toxicity and apoptosis.
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