PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis.
PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A13347
Formula
C15H11NS
Molecular Weight
237.32
CAS Number
4079-26-9
SMILES
C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4
Synonyms
PD 146176, PD-146176, NSC 168807, NSC-168807
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro
DMSO
40 mg/mL (168.54 mM)
Water
Insoluble
Ethanol
17 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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