PFVYLI

Catalog No.: B19174
Hydrophobic penetrating peptide
PFVYLI is a hydrophobic penetrating peptide designed to enhance the delivery of therapeutics, particularly when used to modify doxorubicin-loaded stealth persistent liposomes (PFV-ssls-dox). This compound facilitates cellular uptake and improves the therapeutic efficacy of doxorubicin in breast cancer research applications. Its capacity to penetrate cellular membranes makes it a valuable tool for studying drug delivery mechanisms and optimizing cancer treatment strategies.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPFVYLI is a hydrophobic penetrating peptide designed to enhance the delivery of therapeutics, particularly when used to modify doxorubicin-loaded stealth persistent liposomes (PFV-ssls-dox). This compound facilitates cellular uptake and improves the therapeutic efficacy of doxorubicin in breast cancer research applications. Its capacity to penetrate cellular membranes makes it a valuable tool for studying drug delivery mechanisms and optimizing cancer treatment strategies.
Product Information
Catalog NumB19174
FormulaC40H58N6O8
Molecular Weight750.92
CAS Number1252672-28-8
SequencePro-Phe-Val-Tyr-Leu-Ile
Sequence shorteningPFVYLI
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CC(C)C)=O)NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCCN3)=O)C(C)C)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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