Catalog No.: A12450

p53 Inhibitor


Pifithrin-beta Chemical Structure

CAS NO. 511296-88-1

Pifithrin-beta is a small molecule inhibitor of p53.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • J Priyanga, .et al. A novel indenone derivative selectively induces senescence in MDA-MB-231 (breast adenocarcinoma) cells, Chem Biol Interact, 2020, Nov 1;331:109250 PMID: 32956706

Biological Activity

Pifithrin-beta is a small molecule inhibitor of p53.
In vitro DMSO 24 mg/mL (68.7 mM)
Water Insoluble
Ethanol 3 mg/mL (8.58 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.63 mL 143.15 mL 286.3 mL
0.5 mM 5.73 mL 28.63 mL 57.26 mL
1 mM 2.86 mL 14.31 mL 28.63 mL
5 mM 0.57 mL 2.86 mL 5.73 mL

*The above data is based on the productmolecular weight 349.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12450
Actions Inhibitor
CAS No. 511296-88-1
Formula C16H16N2S.HBr
M. Wt 349.29
Purity >98%

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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