Catalog No.: A12449

p53 inhibitor


Pifithrin-u Chemical Structure

CAS NO. 64984-31-2

inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.

Availability: In stock

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10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $180.00

Special Price $144.00

100 mg

Regular Price: $300.00

Special Price $240.00

10mM * 1mL in DMSO

Regular Price: $68.00

Special Price $54.40

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Biological Activity

inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.
In vitro (25°C) DMSO 33 mg/mL (182.11 mM)
Water 33 mg/mL (182.11 mM)
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 55.18 mL 275.92 mL 551.85 mL
0.5 mM 11.04 mL 55.18 mL 110.37 mL
1 mM 5.52 mL 27.59 mL 55.18 mL
5 mM 1.1 mL 5.52 mL 11.04 mL

*The above data is based on the productmolecular weight 181.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12449
Actions Inhibitor
CAS No. 64984-31-2
Formula C8H7NO2S
M. Wt 181.21
Solubility DMSO
Purity >98%
Synonyms NSC 303580

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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