Pifithrin-u

Catalog No.: A12449

p53 inhibitor

Pifithrin-u

Pifithrin-u Chemical Structure

CAS NO. 64984-31-2

inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$180.00
100 mg
$300.00
10mM * 1mL in DMSO
$68.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL.
Targets
p53
In vitro (25°C) DMSO 36 mg/mL (198.66 mM)
Water <1 mg/mL (<1 mM)
Ethanol 36 mg/mL (198.66 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 55.18 mL 275.92 mL 551.85 mL
0.5 mM 11.04 mL 55.18 mL 110.37 mL
1 mM 5.52 mL 27.59 mL 55.18 mL
5 mM 1.1 mL 5.52 mL 11.04 mL

*The above data is based on the productmolecular weight 181.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12449
Actions Inhibitor
M. Wt 181.21
Formula C8H7NO2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 64984-31-2
Synonyms NSC 303580
SMILES C1=CC=C(C=C1)C#CS(=O)(=O)N

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Pifithrin-u | Pifithrin-u Supplier | purchase Pifithrin-u | Pifithrin-u cost | Pifithrin-u manufacturer | order Pifithrin-u | Pifithrin-u distributor | buy 64984-31-2| 64984-31-2 Supplier | purchase 64984-31-2 | 64984-31-2 cost | 64984-31-2 manufacturer | order 64984-31-2 | 64984-31-2 distributor
Rewards