PRMT5-IN-20

Catalog No.: A26793
PRMT5 Inhibitor
PRMT5-IN-20 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), targeting the methylation of arginine residues on histones and non-histone proteins. This compound exhibits significant anti-tumor activity, making it a valuable tool for cancer research. PRMT5-IN-20 is suitable for studies investigating the role of arginine methylation in various malignancies and the therapeutic potential of targeting PRMT5 in cancer biology.
Grouped product items
Size Price Stock Qty
5mg
$100.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPRMT5-IN-20 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), targeting the methylation of arginine residues on histones and non-histone proteins. This compound exhibits significant anti-tumor activity, making it a valuable tool for cancer research. PRMT5-IN-20 is suitable for studies investigating the role of arginine methylation in various malignancies and the therapeutic potential of targeting PRMT5 in cancer biology.
Product Information
Catalog NumA26793
FormulaC21H21N3
Molecular Weight315.41
CAS Number880813-30-9
SMILESCCN1C2=C(C3=C1C=CC=C3)C=C(CNCC4=CC=CN=C4)C=C2
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