Racecadotril-d5 is a deuterated form of Racecadotril, a neutral endopeptidase (NEP) inhibitor. It exhibits significant inhibition of NEP activity in mouse brain tissues, with reported inhibition constants (Kis) of 4500 nM for Racecadotril and 6.1 nM for its active metabolite, Thiorphan. Racecadotril-d5 serves as a valuable tool for research applications involving pain modulation and gastrointestinal studies, further contributing to the understanding of NEP's role in various biological processes.
Racecadotril-d5 is a deuterated form of Racecadotril, a neutral endopeptidase (NEP) inhibitor. It exhibits significant inhibition of NEP activity in mouse brain tissues, with reported inhibition constants (Kis) of 4500 nM for Racecadotril and 6.1 nM for its active metabolite, Thiorphan. Racecadotril-d5 serves as a valuable tool for research applications involving pain modulation and gastrointestinal studies, further contributing to the understanding of NEP's role in various biological processes.
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