RAD51-IN-9 is a potent inhibitor of RAD51, effectively disrupting the binding of RAD51 to single-stranded DNA with an IC50 of 17.85 μM. This compound demonstrates an LD50 against HEK293 cells of 40.21 μM and is capable of sensitizing cells to the cytotoxic effects of Mitomycin C. RAD51-IN-9 is a valuable tool for research focused on DNA repair mechanisms and the therapeutic targeting of cancer cells.
RAD51-IN-9 is a potent inhibitor of RAD51, effectively disrupting the binding of RAD51 to single-stranded DNA with an IC50 of 17.85 μM. This compound demonstrates an LD50 against HEK293 cells of 40.21 μM and is capable of sensitizing cells to the cytotoxic effects of Mitomycin C. RAD51-IN-9 is a valuable tool for research focused on DNA repair mechanisms and the therapeutic targeting of cancer cells.
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