(S)-KT109 is a selective inhibitor of diacylglycerol lipase β (DAGLβ), exhibiting an IC50 of 39.81 nM. This compound demonstrates lower inhibitory effects on DAGLα, with an IC50 of 794.3 nM, and shows reduced activity against α/β-amidase domain-containing 6 (ABHD6) at an IC50 of 630.9 nM. (S)-KT109 is valuable for research investigating the roles of endocannabinoids in various biological pathways, particularly those involving lipids and neurobiology.
(S)-KT109 is a selective inhibitor of diacylglycerol lipase β (DAGLβ), exhibiting an IC50 of 39.81 nM. This compound demonstrates lower inhibitory effects on DAGLα, with an IC50 of 794.3 nM, and shows reduced activity against α/β-amidase domain-containing 6 (ABHD6) at an IC50 of 630.9 nM. (S)-KT109 is valuable for research investigating the roles of endocannabinoids in various biological pathways, particularly those involving lipids and neurobiology.
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