Total item
Cart Subtotal
$0.00 - Tony Ngo, .et al. Orphan receptor ligand discovery by pickpocketing pharmacological neighbors, Nat Chem Biol, 2017, Feb; 13(2): 235-242 PMID: 27992882
Biological Activity
SB 334867 is a selective non-peptide orexin OX1 receptor antagonist. pKb values are 7.2 and < 5 for inhibition of intracellular Ca2+ release in CHO cells expressing human OX1 and OX2 receptors respectively. Blocks orexin-A induced grooming and feeding following systemic administration in vivo.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.32 mL | 156.58 mL | 313.17 mL |
| 0.5 mM | 6.26 mL | 31.32 mL | 62.63 mL |
| 1 mM | 3.13 mL | 15.66 mL | 31.32 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
*The above data is based on the productmolecular weight 319.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12786 |
|---|---|
| Actions | Antagonist |
| CAS No. | 249889-64-3 |
| Formula | C17H13N5O2 |
| M. Wt | 319.32 |
| Purity | >98% |
| Synonyms | SB334867,SB-334867 |
| SMILES | CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy SB 334867 | SB 334867 Supplier | purchase | cost | manufacturer | order | distributor | buy 249889-64-3| 249889-64-3 Supplier | purchase 249889-64-3 | 249889-64-3 cost | 249889-64-3 manufacturer | order 249889-64-3 | 249889-64-3 distributor
Adooq Quality Guarantee
We promise all products perform as described.