SBE 13 HCl

Catalog No.: A14426

PLK inhibitor

SBE 13 HCl Chemical Structure

CAS NO. 1052532-15-6

SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $64.00

25 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $300.00

Special Price $240.00

10mM * 1mL in DMSO
$100.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SBE 13 HCl is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively).
Targets
PLK1 PLK3 PLK2
200 pM875 nM>66 μM
In vitro DMSO 95 mg/mL (198.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.86 mL 104.3 mL 208.59 mL
0.5 mM 4.17 mL 20.86 mL 41.72 mL
1 mM 2.09 mL 10.43 mL 20.86 mL
5 mM 0.42 mL 2.09 mL 4.17 mL

*The above data is based on the productmolecular weight 479.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14426
Actions Inhibitor
M. Wt 479.4
Formula C24H27ClN2O4.HC
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1052532-15-6
Synonyms SBE-13, SBE 13
SMILES COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl

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