NMS-1286937

Catalog No.: A13045

PLK inhibitor

NMS-1286937

NMS-1286937 Chemical Structure

CAS NO. 1034616-18-6

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.
Targets
PLK1 PLK2 PLK3
2 nM>10 μM>10 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.89 mL 187.79 mL
0.5 mM 3.76 mL 18.78 mL 37.56 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13045
Actions Inhibitor
M. Wt 532.52
Formula C24H27F3N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1034616-18-6
Synonyms NMS1286937, NMS-P937
SMILES CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy NMS-1286937 | NMS-1286937 Supplier | purchase NMS-1286937 | NMS-1286937 cost | NMS-1286937 manufacturer | order NMS-1286937 | NMS-1286937 distributor | buy 1034616-18-6| 1034616-18-6 Supplier | purchase 1034616-18-6 | 1034616-18-6 cost | 1034616-18-6 manufacturer | order 1034616-18-6 | 1034616-18-6 distributor
Rewards