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PLK inhibitor

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Catalog No. A13045

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NMS-1286937 10mg A13045-10
NMS-1286937 25mg A13045-25
NMS-1286937 50mg A13045-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.


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Chemical Information

Catalog Num A13045
Actions Inhibitor
M. Wt 532.52
Formula C24H27F3N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1034616-18-6
Synonyms NMS1286937, NMS-P937

Biological Activity

NMS-1286937 is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity.
2 nM>10 μM>10 μM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.78 mL 93.89 mL 187.79mL
0.5 mM 3.76 mL 18.78 mL 37.56 mL
1 mM 1.88 mL 9.39 mL 18.78 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 532.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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