Catalog No.: A10442
PLK Inhibitor
GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1).
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GSK461364 5mg
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Biological Activity
Discription GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1).
Target Value
Product Information
Catalog Num A10442
Formula C27H28F3N5O2S
Molecular Weight 543.6
CAS Number 929095-18-1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 9 mg/mL (16.55 mM)
Water Insoluble
Ethanol 27 mg/mL (49.66 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.98 mL 183.96 mL
0.5 mM 3.68 mL 18.4 mL 36.79 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL
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