SDH-IN-6

Catalog No.: A28103
SDH Inhibitor
SDH-IN-6 is a potent inhibitor of succinate dehydrogenase (SDH). This compound demonstrates significant antifungal activity against Valsa mali, exhibiting an EC50 value of 1.77 mg/L. It is a valuable research tool for investigating the role of SDH in fungal metabolism and potential therapeutic approaches for treating fungal infections.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSDH-IN-6 is a potent inhibitor of succinate dehydrogenase (SDH). This compound demonstrates significant antifungal activity against Valsa mali, exhibiting an EC50 value of 1.77 mg/L. It is a valuable research tool for investigating the role of SDH in fungal metabolism and potential therapeutic approaches for treating fungal infections.
Product Information
Catalog NumA28103
FormulaC18H17ClF2N4OS
Molecular Weight410.87
CAS Number3010257-33-4
SMILESClC(C=C1)=CC=C1C(C2=NC(C)=C(S2)C)NC(C(C(C(F)F)=N3)=CN3C)=O
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