Shizukaol B is an anti-inflammatory agent derived from the lindenane-type dimeric sesquiterpene found in Chloranthus henryi. This compound demonstrates significant inhibitory effects against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells, effectively reducing nitric oxide production and downregulating the expression of pro-inflammatory markers such as iNOS, COX-2, TNF-α, and IL-1β. Shizukaol B is suitable for research applications focused on neuroinflammation and related therapeutic strategies.
Shizukaol B is an anti-inflammatory agent derived from the lindenane-type dimeric sesquiterpene found in Chloranthus henryi. This compound demonstrates significant inhibitory effects against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells, effectively reducing nitric oxide production and downregulating the expression of pro-inflammatory markers such as iNOS, COX-2, TNF-α, and IL-1β. Shizukaol B is suitable for research applications focused on neuroinflammation and related therapeutic strategies.
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