SIRT6-IN-3

Name: SIRT6-IN-3
Brand: Adooq Bioscience
SKU: A25886
Rating: 5 (288 reviews)

Catalog No.: A25886

SIRT6 Inhibitor

SIRT6-IN-3 is a selective inhibitor of SIRT6, exhibiting an IC50 of 7.49 μM. This compound effectively inhibits the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and promotes apoptosis. Additionally, SIRT6-IN-3 enhances the sensitivity of cancer cells to gemcitabine by obstructing the DNA damage repair pathway, making it a valuable tool in pancreatic cancer research.

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Grouped product items
Size	Price	Stock
5mg	$410.00	In stock
10mg	$670.00	In stock
25mg	$1,345.00	In stock
50mg	$2,130.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper

Biological Activity

Description	SIRT6-IN-3 is a selective inhibitor of SIRT6, exhibiting an IC50 of 7.49 μM. This compound effectively inhibits the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and promotes apoptosis. Additionally, SIRT6-IN-3 enhances the sensitivity of cancer cells to gemcitabine by obstructing the DNA damage repair pathway, making it a valuable tool in pancreatic cancer research.

Product Information

Catalog Num	A25886
Formula	C21H30Br3ClN6S
Molecular Weight	673.73
CAS Number	3023471-40-8
SMILES	BrC1=C(Br)NC(C2=NC=CC3=C2N=CN3CCCCCCS/C(N(C)C)=[N+](C)\C)=C1.Cl.[Br-]

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