SR-1114

Name: SR-1114
Brand: Adooq Bioscience
SKU: A24451
Rating: 5 (288 reviews)

Catalog No.: A24451

PROTAC ENL degrader

SR-1114 is a first-in-class PROTAC degrader targeting ENL. It induces rapid, cereblon (CRBN)-dependent degradation of ENL with DC₅₀ values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells.

Skip to the end of the images gallery

SR-1114 2769141-82-2 PROTAC ENL degrader

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
1mg	$288.00	In stock
5mg	$864.00	In stock
10mg	$1,472.00	In stock
50mg	$4,416.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Research use only. We do not sell to patients.

Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper

Biological Activity

Description	SR-1114 is a first-in-class PROTAC degrader targeting ENL. It induces rapid, cereblon (CRBN)-dependent degradation of ENL with DC₅₀ values of 150 nM in MV4;11 cells, 311 nM in MOLM-13 cells, and 1.65 μM in OCI/AML-2 cells.

Product Information

Catalog Num	A24451
Formula	C39H42N8O11S
Molecular Weight	830.86
CAS Number	2769141-82-2
SMILES	O=C(NCCOCCOCCNS(=O)(NC1=CC=CC(C2=CN3C=C(C=CC3=N2)C(NC4CCC4)=O)=C1)=O)COC5=CC=CC6=C5C(N(C6=O)C7CCC(NC7=O)=O)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂