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Biological Activity

SRT 1720 is a selective activator of human SIRT1 (EC1.5 = 0.16 μM) versus the closest sirtuin homologues, SIRT2 and SIRT3 (SIRT2: EC1.5 = 37 uM; SIRT3: EC1.5 > 300 uM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.48 mL 212.97 mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15247
Actions Activator
M. Wt 469.56
Formula C25H23N7OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 925434-55-5
Synonyms SRT-1720, SRT1720
SMILES C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5

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