Succinate dehydrogenase-IN-1 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.94 μM and a KD of 22.4 μM. This compound demonstrates significant antifungal activity against various pathogens, including Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 values of 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively. Succinate dehydrogenase-IN-1 can be utilized in studies focusing on fungal infections and metabolic pathways involving SDH inhibition.
Succinate dehydrogenase-IN-1 is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.94 μM and a KD of 22.4 μM. This compound demonstrates significant antifungal activity against various pathogens, including Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 values of 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively. Succinate dehydrogenase-IN-1 can be utilized in studies focusing on fungal infections and metabolic pathways involving SDH inhibition.
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