Tat-SERT-15C

Catalog No.: A65297
Antidepressant Peptide
Tat-SERT-15C is an antidepressant peptide that modulates the serotonin transporter (SERT) and nitric oxide synthase (nNOS) interaction. This peptide decreases the SERT-nNOS complex, leading to enhanced SERT expression. Tat-SERT-15C has demonstrated efficacy in reversing depression-like behaviors induced by chronic unpredictable mild stress, making it a valuable tool for research into the mechanisms of depression and potential therapeutic interventions.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTat-SERT-15C is an antidepressant peptide that modulates the serotonin transporter (SERT) and nitric oxide synthase (nNOS) interaction. This peptide decreases the SERT-nNOS complex, leading to enhanced SERT expression. Tat-SERT-15C has demonstrated efficacy in reversing depression-like behaviors induced by chronic unpredictable mild stress, making it a valuable tool for research into the mechanisms of depression and potential therapeutic interventions.
Product Information
Catalog NumA65297
FormulaC131H229N51O36S2
Molecular Weight3158.67
CAS Number2614435-43-5
SequenceTyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Thr-Pro-Thr-Glu-Ile-Pro-Cys-Gly-Asp-Ile-Arg-Met-Asn-Ala-Val
Sequence shorteningYGRKKRRQRRRTPTEIPCGDIRMNAV
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