TCO-PEG3-Biotin is a cleavable linker designed for antibody-drug conjugate (ADC) synthesis, featuring a three-unit polyethylene glycol (PEG) backbone. This compound includes a trans-cyclooctene (TCO) moiety that facilitates click chemistry through an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules. TCO-PEG3-Biotin is valuable in conjugating biomolecules, enabling targeted drug delivery and enhancing therapeutic efficacy in various biological research applications.
TCO-PEG3-Biotin is a cleavable linker designed for antibody-drug conjugate (ADC) synthesis, featuring a three-unit polyethylene glycol (PEG) backbone. This compound includes a trans-cyclooctene (TCO) moiety that facilitates click chemistry through an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing molecules. TCO-PEG3-Biotin is valuable in conjugating biomolecules, enabling targeted drug delivery and enhancing therapeutic efficacy in various biological research applications.
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