Tenovin-D3 hydrochloride

Catalog No.: A57001
sirtuin SirT2 Inhibitor
Tenovin-D3 hydrochloride is a selective inhibitor of the sirtuin SirT2, which plays a crucial role in cellular regulation. This compound has been shown to enhance the expression of p21 (CDKN1A) independently of the p53 pathway. It is suitable for research applications focused on aging, cancer biology, and the modulation of cellular stress responses to explore the therapeutic potential of sirtuin inhibition.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTenovin-D3 hydrochloride is a selective inhibitor of the sirtuin SirT2, which plays a crucial role in cellular regulation. This compound has been shown to enhance the expression of p21 (CDKN1A) independently of the p53 pathway. It is suitable for research applications focused on aging, cancer biology, and the modulation of cellular stress responses to explore the therapeutic potential of sirtuin inhibition.
Product Information
Catalog NumA57001
FormulaC22H27Cl3N4O3S
Molecular Weight533.90
CAS Number1258283-70-3
SMILESO=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC(Cl)=C(OC)C(Cl)=C2.[H]Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2